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[–] Seventh_Jim 0 points 2 points (+2|-0) ago 

The therapy helps avoid a bad trip. Psilocybin functionallycures depression for 8-12 months.

Basically the brain loves patterns. Depression is a repeated pattern of misery. Psilocybin scrambles all patterns temporarily, while metabolizing to a sertonin promoter. You stop being stuck in a rut at the same time you begin feeling positivity for the first time in a while. Good medicine.

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[–] Gringojones 0 points 1 point (+1|-0) ago 

I've only done acid once but it gave me a much calmer outlook for several months afterwards. I would imagine its a similar process.

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[–] Seventh_Jim ago 

I haven't looked at the metabolites of lsd. I think it doesn't behave as a serotonin agonist, so works well for anxiety and ptsd, but not as much for depression.

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[–] Maroonsaint ago 

Alcohol is as well.