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[–] Delusion_of_Adequacy 0 points 4 points (+4|-0) ago 

Although this definitely makes life a lot harder, due to low IQ, incredibly high tolerance to pain and a truly insatiable appetite, and it is actually caused by genetics, it's not the end of the world:

With the recent benefits of early diagnosis and ongoing interventions, the obesity rate among children with Prader–Willi Syndrome has decreased to be similar to the typical population. With behavioural therapy and other treatments, the effects of the syndrome can be reduced.

source

So no, generally it isn't.