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[–] ChicagoSunroof [S] 0 points 27 points (+27|-0) ago 

Here a non-PDF version

http://www.nejm.org/doi/full/10.1056/NEJM199212313272701#t=article

The last paragraph says:

In conclusion, all the obese subjects we studied who had a history of self-reported diet resistance had appropriate energy expenditure, but they misreported their actual food intake and physical activity.

Fattys gonna fat!

They used "Doubly Labeled" water to determine actual metabolism and energy intake. I'm still not 100% sure I understand the chemistry and physics behind this.

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[–] ifdeltadout 0 points 22 points (+22|-0) ago 

With regards to the doubly labelled water, what they did was give the subjects a dose of radio-labelled water, partly labelled with 18O and partly with 2H, and then they looked at the amounts of both isotopes in the subjects' urine in the following days. Because of how metabolism works, all of the 2H gets eliminated from the body through the urine, but the 18O is eliminated in the urine and as CO2. So by comparing the relative elimination rates of both elements in the urine, you can figure out how much CO2 is being produced, and thus the metabolic rate.

I'm not sure how much sense that makes, or if you even really wanted to know more, but I hope it helps!

Source: this study they cited explains the methods better: http://ajpregu.physiology.org/content/ajpregu/250/5/R823.full.pdf (might be behind a paywall?)

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[–] GenevieveJenkins 0 points 4 points (+4|-0) ago  (edited ago)

I watched some video the other day that said that when fat is "burned" it turns into CO2 and H2O. So does this mean that the 18O essentially tracks how much fat is burned?

Edit: Oh and the link is not behind a paywall :)

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[–] anticlutch 0 points 3 points (+3|-0) ago 

Wait... So what you're saying is I don't have a magical metabolism that makes me better than fat people? I'm simply better than fat people? That's oppressive! /s

[–] [deleted] 0 points 1 points (+1|-0) ago 

[Deleted]

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[–] physicscat 0 points 8 points (+8|-0) ago 

"Misreported" AKA lying their ass off.

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[–] 1025888 0 points 3 points (+3|-0) ago 

Watch secret eaters. It seems like they honestly have no idea. Like they're just dumb as fuck

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[–] dotty 0 points 26 points (+26|-0) ago 

Also, according to Google Scholar, this article has been cited 1,065 times by other related academic articles since its publication in 1992. That's actually pretty high. I do research for a living, and that is a always a good sign for determining whether the article is still deemed accurate. When I filtered it to "since 2015", 32 articles have cited it this year.

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[–] CountZero 0 points 14 points (+14|-0) ago 

May the scientific shitlording continue!

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[–] Senescence 0 points 12 points (+12|-0) ago 

Honestly, science is the best at shitlording. It's fact whether fats want to admit it or not.

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[–] SamPitcher 0 points 13 points (+13|-0) ago 

How unsurprised are we?

As Dr House says people lie. fatties lie about how much they eat. They lie to themselves, they lie to their doctors, they lie to their trainers, they lie to their families

[–] [deleted] 0 points 5 points (+5|-0) ago 

[Deleted]

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[–] RunningShark 0 points 1 points (+1|-0) ago 

I wonder if "I now pronounce you chuck and larry" stole that from house

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[–] mmmmdonuts 0 points 3 points (+3|-0) ago  (edited ago)

I for one, am shocked!

NOT

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[–] Meadow 0 points 1 points (+1|-0) ago 

The only thing I'm genuinely surprised about is the sheer amount of denial here. Like... holy shit.

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[–] skittlesforhair 0 points 9 points (+9|-0) ago 

But...but... guhnetics?

[–] [deleted] 0 points 12 points (+12|-0) ago 

[Deleted]

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[–] skittlesforhair 0 points 6 points (+6|-0) ago 

Thanks patriarchy!

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[–] honormyacanthosis 0 points 5 points (+5|-0) ago 

Scientifically-tested, peer-reviewed evidence, in one of the world's top medical journals, that 100% of fat people are liars.

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[–] j095 0 points 1 points (+1|-0) ago 

100% of fat people who blame anyone but themselves are liars.

100% of fat people are disgusting and lazy though.

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[–] MuhPoopinSpoon 0 points 5 points (+5|-0) ago 

I would love to see then all sat down in a meeting room while someone goes onstage to explain they have been been proven to be liars.

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[–] text_inputter 0 points 7 points (+7|-0) ago 

You'd love the show secret eaters then. You've essentially stated the entire "plot" of the show.

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[–] LordLord_IAmShitLord 0 points 4 points (+4|-0) ago 

They will still stick to their guns.

"I know better than you what I ate"

"It doesn't prove anything, I've been on a diet for the last 10 years - I'm allowed to cheat once in a while"

You know, the typical hamlogic

[–] [deleted] 0 points 4 points (+4|-0) ago 

[Deleted]

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[–] throwaway4021 0 points 1 points (+1|-0) ago 

Yep, the control group were obese too of course, just they didn't claim to be "diet resistant."

The 224 subjects who met these criteria were screened for a history of diet resistance, arbitrarily defined as a current intake of less than 1200 kcal per day as reported on three-day records of food consumption; weight stability (within a range of 3 kg) for the previous six months; and a history of failure to lose weight while following a hypocaloric diet. The 16 subjects who met these criteria were considered for entry into the diet-resistant group (group 1); the remaining 208 subjects were assigned to the control group (group 2).

But both group 1 and group 2 under-reported but the data was only significant in the smaller group.

The energy intake reported by the subjects in group 1 during the 14-day study period was 1028±148 kcal per day, whereas their actual energy intake was 2081±522 kcal per day. Thus, these subjects significantly (P<0.05) underreported their energy intake by a group mean of 1053 kcal per day, or a mean for individual subjects of 47±16 percent

The energy intake reported by the six subjects in group 2 was 1694±364 kcal per day, and their total energy expenditure was 2647±650 kcal per day. Their actual intake was 2386±775 kcal per day. Thus, individual subjects in this group also underreported their energy intake (by 19±38 percent; P not significant).

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