What is cancer? Cancer is not uncontrolled growth or cell divisions, that was the old way of thinking. Today, we see that there are many hallmarks to cancer and in each hallmark, something unique happens, sort of like promoters. So, the way I think of cancer is that it is a failure of homeostasis. So how does fat cows relate to cancer?
One way is our innate immune system is not designed to handle chronic infections but only acute infection and then the body goes its merry way. However, one of the hallmark of cancer is "inflammation." During inflammation, lot of things are happening at the target site at a high rate, and sometimes some of these key proteins, chemicals etc might not function properly and dna transcription can lead to errors, the possibility of misshap is increased. There are checks and balances at stages for DNA transcription by special proteins known as p53 and others. Being fat cow will increase the risk of injury, leading to inflammation and creating a environment where cancer can develop. Plus, as I stated earlier, cancer is a failure of homeostasis, being a fat cow does lead to stress on the body, which leads to heightened immune response, which also leads to cancer development.
This is very simplified explanation but there are hallmarks of cancer on can read on and shitload of NIH research. Here is direction if you all want to explore further. Anyhow, my research paper was on how gut microbiota may affect the development of cancer, and all research points to that it does. Its another emerging hallmark of cancer just like obesity.
http://www.cell.com/trends/endocrinology-metabolism/fulltext/S1043-2760(16)30107-2
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[–] Captain_Butt_Naked [S] 0 points 2 points 2 points (+2|-0) ago
Since there are multiple types of microbes(near 40 trillion in the body) which microbe culture is promoted due to creating an environment that benefits specific type of microbe due to the gut content? When we look at that we see that gut environment effects immune homeostasis. There is constant back and forth suppressing and promoting (fighting-balancing act) due to byproducts created by the microbes. Further, gastrointestinal tract provides the largest surface area in the human body where microbes and their byproducts interacts with the immune system. When we look at breast cancer, we see increased specific type of bacterial transplantation occuring near the mammary glands. When we transplant gut contents that experiments show to promote cancer, we see double the rate occurring at experiments. Anyhow..if you are interested, read the 10 hallmarks.