Personally, I like to see how Trump is going after NAFTA, which was meant as a way for countries like Mexico to feed off our economy and dump a bunch of cheap labor on our country and to take jobs from it. Its a bit more complex than this, but whenever that is the foundation it means things are not good.
Canada is probably more internationalized than we or Mexico are in fact. They have tons of Indians and Chinese working in their informatics sector and they are forming tighter connections with China and were the ones who got real upset when Trump started enacting Tariffs on Chinese imports. Canada's internationalization is relatively niche though. The main issue with them is the government interfering in their oil industry, but Alberta is essentially seceding from the Union.
NAFTA would probably best be rewired so we can tape in the local economies of certain parts of Canada, but in essence there is no need to remain tied to something that does not benefit us and just ties us down to other countries that either suck or are internationalizing. I think Trump is essentially going to try to work a more fine-tuned deal with Canada, where he offers them the world and he gets an island and they will end up rejecting it. Canadians are probably stupider then we are. All those damn Frenchmen and Irishmen. Haha.