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[–] RodnamPosren ago 

Interesting idea. A lot of different angles to take and parallels that might be drawn.

The shipper’s guild being addicted to the spice for travel (spice being crucial to the supply chain)... the abilities of the mentat class and the limitations of the vision (youth elixirs a poor substitute for real youth)... how spice in everything in the world, except the imported food the upper class eat (taunting force of evil down to the lowest levels)...

Perhaps I’m pushing the idea to its limits in wondering of meaning in Paul’s assuming his destiny by becoming the Kwisatz Haderach... lots of savior/religious themes for sure. I don’t think he was outright addicted to spice, just that it was in everything and he was affected in as all who taste spice do... but my memory may not serve tho