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[–] SavageSeasons 1 point -1 points (+0|-1) ago 

The main difference between cross breading and GMO is that cross breeding is the mating of two organisms from two breeds whereas GMOs are the organisms whose genetic material is altered by genetic engineering. The main advantage of cross-breeding is to mate two genetically-related organisms that are never crossed naturally. At the same time, genetic engineering introduces some tremendous and elite qualities to GMO.